Obesity-associated gene FTO rs9939609 polymorphism in relation to the risk of tuberculosis
نویسندگان
چکیده
منابع مشابه
Obesity-associated gene FTO rs9939609 polymorphism in relation to the risk of tuberculosis
BACKGROUND Obesity is known to affect cell-mediated immune responses. Recent studies have revealed that genetic polymorphisms in the fat mass and obesity associated (FTO) gene are related to human obesity. We hypothesize that this gene may also play a role in the risk of immune-related infectious diseases such as tuberculosis. METHODS This case-control study included 1625 pulmonary tuberculos...
متن کاملRelationship between rs9939609 Polymorphism of FTO Gene, Diabetes Mellitus and Tuberculosis
Abstract Tuberculosis and diabetes mellitus are the most important reasons in mortality all over the world. It’s clear that reviewing of relationship between Tuberculosis (TB) and diabetes mellitus (DM) is necessary; on the other hand it’s found that FTO gene has the positive relationship with metabolic issues. Therefore, it’s necessary pay attention to the above and danger...
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15 صفحه اولThe FTO Gene rs9939609 Polymorphism Predicts Risk of Cardiovascular Disease: A Systematic Review and Meta-Analysis
OBJECTIVE Genome-wide association studies have shown that variance in the fat mass- and obesity- associated gene (FTO) is associated with risk of obesity in Europeans and Asians. Since obesity is associated with an increased risk of cardiovascular disease (CVD), several studies have investigated the association between variant in the FTO gene and CVD risk, with inconsistent results. In this stu...
متن کاملThe FTO gene rs9939609 obesity-risk allele and loss of control over eating.
BACKGROUND Children with rs9939609 FTO variant alleles (homozygous = AA and heterozygous = AT) are predisposed to greater adiposity than are those with 2 wild-type alleles (TT). OBJECTIVE Because FTO is highly expressed in hypothalamic regions that are important for appetite, FTO genotype may affect energy balance by influencing eating behavior. Loss of control (LOC) eating, a behavior common...
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ژورنال
عنوان ژورنال: BMC Infectious Diseases
سال: 2014
ISSN: 1471-2334
DOI: 10.1186/preaccept-1680568373103395